Chiral Recognition of Homochiral Poly (amidoamine) Dendrimers Substituted with R- and S-Glycidol by Keratinocyte (HaCaT) and Squamous Carcinoma (SCC-15) Cells In Vitro

The generation 2 and 3 poly(amidoamine) dendrimers (PAMAM G2 and G3) were converted into N-(2,3-dihydroxy)propyl derivatives by the addition of enantiomerically pure S- and R-glycidol. The homochiral dendrimers bind to HaCaT and SCC-15 cell membranes with an R/S glycidol enantioselectivity ratio of...

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Detalles Bibliográficos
Autores principales: Malinga-Drozd, Małgorzata, Uram, Łukasz, Wróbel, Konrad, Wołowiec, Stanisław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037736/
https://www.ncbi.nlm.nih.gov/pubmed/33801610
http://dx.doi.org/10.3390/polym13071049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037736/
https://www.ncbi.nlm.nih.gov/pubmed/33801610
http://dx.doi.org/10.3390/polym13071049

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