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Deciphering the Methylation Landscape in Breast Cancer: Diagnostic and Prognostic Biosignatures through Automated Machine Learning

SIMPLE SUMMARY: Breast cancer (BrCa) is characterized by aberrant DNA methylation. We leveraged high-throughput methylation data from BrCa and normal breast tissues and identified 11,176 to 27,786 differentially methylated genes (DMGs) against clinically relevant end-points. Innovative automated mac...

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Detalles Bibliográficos
Autores principales: Panagopoulou, Maria, Karaglani, Makrina, Manolopoulos, Vangelis G., Iliopoulos, Ioannis, Tsamardinos, Ioannis, Chatzaki, Ekaterini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037759/
https://www.ncbi.nlm.nih.gov/pubmed/33918195
http://dx.doi.org/10.3390/cancers13071677