The Effect of Oxidized Dopamine on the Structure and Molecular Chaperone Function of the Small Heat-Shock Proteins, αB-Crystallin and Hsp27

Oxidation of the neurotransmitter, dopamine (DA), is a pathological hallmark of Parkinson’s disease (PD). Oxidized DA forms adducts with proteins which can alter their functionality. αB-crystallin and Hsp27 are intracellular, small heat-shock molecular chaperone proteins (sHsps) which form the first...

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Detalles Bibliográficos
Autores principales: Hayashi, Junna, Ton, Jennifer, Negi, Sparsh, Stephens, Daniel E. K. M., Pountney, Dean L., Preiss, Thomas, Carver, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037807/
https://www.ncbi.nlm.nih.gov/pubmed/33918165
http://dx.doi.org/10.3390/ijms22073700

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037807/
https://www.ncbi.nlm.nih.gov/pubmed/33918165
http://dx.doi.org/10.3390/ijms22073700

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