Cargando…

The Effect of Oxidized Dopamine on the Structure and Molecular Chaperone Function of the Small Heat-Shock Proteins, αB-Crystallin and Hsp27

Oxidation of the neurotransmitter, dopamine (DA), is a pathological hallmark of Parkinson’s disease (PD). Oxidized DA forms adducts with proteins which can alter their functionality. αB-crystallin and Hsp27 are intracellular, small heat-shock molecular chaperone proteins (sHsps) which form the first...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hayashi, Junna, Ton, Jennifer, Negi, Sparsh, Stephens, Daniel E. K. M., Pountney, Dean L., Preiss, Thomas, Carver, John A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037807/ https://www.ncbi.nlm.nih.gov/pubmed/33918165 http://dx.doi.org/10.3390/ijms22073700

Ejemplares similares

Site-Specific Glycation of Human Heat Shock Protein (Hsp27) Enhances Its Chaperone Activity
por: Mukherjee, Somnath, et al.
Publicado: (2023)

Heat shock-induced chaperoning by Hsp70 is enabled in-cell
por: Guin, Drishti, et al.
Publicado: (2019)

Heat shock protein 27 (HSP27): biomarker of disease and therapeutic target
por: Vidyasagar, Aparna, et al.
Publicado: (2012)

Hsp40 Couples with the CSPα Chaperone Complex upon Induction of the Heat Shock Response
por: Gibbs, Sarah J., et al.
Publicado: (2009)

The Chaperone System in Breast Cancer: Roles and Therapeutic Prospects of the Molecular Chaperones Hsp27, Hsp60, Hsp70, and Hsp90
por: Alberti, Giusi, et al.
Publicado: (2022)

The role of small heat-shock protein αB-crystalline (HspB5) in COPD pathogenesis
por: Cherneva, Radostina V, et al.
Publicado: (2012)

Revisiting the Old Data of Heat Shock Protein 27 Expression in Squamous Cell Carcinoma: Enigmatic HSP27, More Than Heat Shock
por: Zheng, Shutao, et al.
Publicado: (2022)

Localization of Heat Shock Protein 27 (Hsp27) in the Rat Gingiva and its Changes with Tooth Eruption
por: Sasaki, Au, et al.
Publicado: (2011)

Expression of one important chaperone protein, heat shock protein 27, in neurodegenerative diseases
por: Zhang, Xuekai, et al.
Publicado: (2014)

Local unfolding of the HSP27 monomer regulates chaperone activity
por: Alderson, T. Reid, et al.
Publicado: (2019)

Localization and Expression of Hsp27 and αB-Crystallin in Rat Primary Myocardial Cells during Heat Stress In Vitro
por: Tang, Shu, et al.
Publicado: (2013)

Heat shock resistance conferred by expression of the human HSP27 gene in rodent cells
Publicado: (1989)

The heat shock protein Hsp27 controls mitochondrial function by modulating ceramide generation
por: Boyd, Rowan A., et al.
Publicado: (2023)

Expression of Heat Shock Protein-27 (Hsp27) and P38MAPK in Esophageal Squamous Cell Carcinoma
por: Zhang, Yan, et al.
Publicado: (2017)

Expression of the murine small heat shock proteins hsp 25 and alpha B crystallin in the absence of stress
Publicado: (1993)

Investigating the Chaperone Properties of a Novel Heat Shock Protein, Hsp70.c, from Trypanosoma brucei
por: Burger, Adélle, et al.
Publicado: (2014)

Tissue-specific expression of the heat shock protein HSP27 during Drosophila melanogaster development
Publicado: (1990)

A Targetable Molecular Chaperone Hsp27 Confers Aggressiveness in Hepatocellular Carcinoma
por: Zhang, Yurong, et al.
Publicado: (2016)

Molecular chaperone Hsp27 regulates the Hippo tumor suppressor pathway in cancer
por: Vahid, Sepideh, et al.
Publicado: (2016)

Heat‐shock protein 27 (HSP27, HSPB1) is synthetic lethal to cells with oncogenic activation of MET, EGFR and BRAF
por: Konda, John D., et al.
Publicado: (2017)

Chaperone-Based Therapeutic Target Innovation: Heat Shock Protein 70 (HSP70) for Type 2 Diabetes Mellitus
por: Mulyani, W. Riski Widya, et al.
Publicado: (2020)

Effect of Heat Shock Preconditioning on Pressure Injury Prevention via Hsp27 Upregulation in Rat Models
por: Xu, Huiwen, et al.
Publicado: (2022)

DNAJC9 integrates heat shock molecular chaperones into the histone chaperone network
por: Hammond, Colin M., et al.
Publicado: (2021)

Overexpression of heat shock protein 27 (HSP27) increases gemcitabine sensitivity in pancreatic cancer cells through S-phase arrest and apoptosis
por: Guo, Yang, et al.
Publicado: (2015)

Proteomic Characterization of Annexin l (ANX1) and Heat Shock Protein 27 (HSP27) as Biomarkers for Invasive Hepatocellular Carcinoma Cells
por: Wang, Ruo-Chiau, et al.
Publicado: (2015)

Hsp110 Chaperones Control Client Fate Determination in the Hsp70–Hsp90 Chaperone System
por: Mandal, Atin K., et al.
Publicado: (2010)

Glutathionylation of the Bacterial Hsp70 Chaperone DnaK Provides a Link between Oxidative Stress and the Heat Shock Response
por: Perrett, Sarah
Publicado: (2016)

Subcellular Location of Piscirickettsia salmonis Heat Shock Protein 60 (Hsp60) Chaperone by Using Immunogold Labeling and Proteomic Analysis
por: Oliver, Cristian, et al.
Publicado: (2020)

Targeting heat shock protein 27 (HspB1) interferes with bone metastasis and tumour formation in vivo
por: Gibert, B, et al.
Publicado: (2012)

Clinicopathological Significance of Heat Shock Protein (HSP) 27 Expression in Gastric Cancer: A Updated Meta-Analysis
por: Liu, Tong, et al.
Publicado: (2020)

Expression of Inducible Heat Shock Proteins Hsp27 and Hsp70 in the Visual Pathway of Rats Subjected to Various Models of Retinal Ganglion Cell Injury
por: Chidlow, Glyn, et al.
Publicado: (2014)

Role of Heat Shock Proteins (HSP70 and HSP90) in Viral Infection
por: Lubkowska, Anna, et al.
Publicado: (2021)

Thermotolerance and molecular chaperone function of the small heat shock protein HSP20 from hyperthermophilic archaeon, Sulfolobus solfataricus P2
por: Li, Dong-Chol, et al.
Publicado: (2011)

RNAi-dependent heterochromatin assembly in fission yeast Schizosaccharomyces pombe requires heat-shock molecular chaperones Hsp90 and Mas5
por: Okazaki, Kosuke, et al.
Publicado: (2018)

Characterization of the Relationship between the Chaperone and Lipid-Binding Functions of the 70-kDa Heat-Shock Protein, HspA1A
por: Smulders, Larissa, et al.
Publicado: (2020)

Knock Down of Heat Shock Protein 27 (HspB1) Induces Degradation of Several Putative Client Proteins
por: Gibert, Benjamin, et al.
Publicado: (2012)

In Vivo Substrates of the Lens Molecular Chaperones αA-Crystallin and αB-Crystallin
por: Andley, Usha P., et al.
Publicado: (2014)

Alterations of the Hsp70/Hsp90 chaperone and the HOP/CHIP co-chaperone system in cancer
por: Ruckova, Eva, et al.
Publicado: (2012)

Heat Shock Protein 27 (HSP27) as a Potential Prognostic Marker: Immunohistochemical Analysis of Oral Epithelial Dysplasia and Oral Squamous Cell Carcinoma
por: Ramalingam, Karthikeyan, et al.
Publicado: (2022)

Analysis of the Dominant Effects Mediated by Wild Type or R120G Mutant of αB-crystallin (HspB5) towards Hsp27 (HspB1)
por: Simon, Stéphanie, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_5u2k46snoo5aitvh5gnq2ar3r9