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Pathological Relationship between Intracellular Superoxide Metabolism and p53 Signaling in Mice

Intracellular superoxide dismutases (SODs) maintain tissue homeostasis via superoxide metabolism. We previously reported that intracellular reactive oxygen species (ROS), including superoxide accumulation caused by cytoplasmic SOD (SOD1) or mitochondrial SOD (SOD2) insufficiency, induced p53 activat...

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Detalles Bibliográficos
Autores principales: Watanabe, Kenji, Shibuya, Shuichi, Ozawa, Yusuke, Toda, Toshihiko, Shimizu, Takahiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037821/
https://www.ncbi.nlm.nih.gov/pubmed/33805584
http://dx.doi.org/10.3390/ijms22073548