Cargando…

Pathological Relationship between Intracellular Superoxide Metabolism and p53 Signaling in Mice

Intracellular superoxide dismutases (SODs) maintain tissue homeostasis via superoxide metabolism. We previously reported that intracellular reactive oxygen species (ROS), including superoxide accumulation caused by cytoplasmic SOD (SOD1) or mitochondrial SOD (SOD2) insufficiency, induced p53 activat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Watanabe, Kenji, Shibuya, Shuichi, Ozawa, Yusuke, Toda, Toshihiko, Shimizu, Takahiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037821/ https://www.ncbi.nlm.nih.gov/pubmed/33805584 http://dx.doi.org/10.3390/ijms22073548

Ejemplares similares

Sod1 Loss Induces Intrinsic Superoxide Accumulation Leading to p53-Mediated Growth Arrest and Apoptosis
por: Watanabe, Kenji, et al.
Publicado: (2013)

Xanthine Oxidoreductase-Mediated Superoxide Production Is Not Involved in the Age-Related Pathologies in Sod1-Deficient Mice
por: Shibuya, Shuichi, et al.
Publicado: (2021)

Superoxide Dismutase 1 Loss Disturbs Intracellular Redox Signaling, Resulting in Global Age-Related Pathological Changes
por: Watanabe, Kenji, et al.
Publicado: (2014)

Palladium and Platinum Nanoparticles Attenuate Aging-Like Skin Atrophy via Antioxidant Activity in Mice
por: Shibuya, Shuichi, et al.
Publicado: (2014)

Acai Extract Transiently Upregulates Erythropoietin by Inducing a Renal Hypoxic Condition in Mice
por: Shibuya, Shuichi, et al.
Publicado: (2020)

Resveratrol Derivative-Rich Melinjo Seed Extract Attenuates Skin Atrophy in Sod1-Deficient Mice
por: Watanabe, Kenji, et al.
Publicado: (2015)

Royal Jelly Delays Motor Functional Impairment During Aging in Genetically Heterogeneous Male Mice
por: Okumura, Nobuaki, et al.
Publicado: (2018)

Mitochondrial superoxide in osteocytes perturbs canalicular networks in the setting of age-related osteoporosis
por: Kobayashi, Keiji, et al.
Publicado: (2015)

Probiotic Lactobacillus paracasei A221 improves the functionality and bioavailability of kaempferol-glucoside in kale by its glucosidase activity
por: Shimojo, Yosuke, et al.
Publicado: (2018)

Cytoplasmic superoxide radical: a possible contributing factor to intracellular Aβ oligomerization in Alzheimer disease
por: Murakami, Kazuma, et al.
Publicado: (2012)

Senescence marker protein-30/superoxide dismutase 1 double knockout mice exhibit increased oxidative stress and hepatic steatosis
por: Kondo, Yoshitaka, et al.
Publicado: (2014)

Mechanical overloading causes mitochondrial superoxide and SOD2 imbalance in chondrocytes resulting in cartilage degeneration
por: Koike, Masato, et al.
Publicado: (2015)

Natural Compounds That Enhance Motor Function in a Mouse Model of Muscle Fatigue
por: Shibuya, Shuichi, et al.
Publicado: (2022)

Topical Application of Trisodium Ascorbyl 6-Palmitate 2-Phosphate Actively Supplies Ascorbate to Skin Cells in an Ascorbate Transporter-Independent Manner
por: Shibuya, Shuichi, et al.
Publicado: (2017)

Antioxidants Improve the Phenotypes of Dilated Cardiomyopathy and Muscle Fatigue in Mitochondrial Superoxide Dismutase-Deficient Mice
por: Koyama, Hirofumi, et al.
Publicado: (2013)

Brain-Specific Superoxide Dismutase 2 Deficiency Causes Perinatal Death with Spongiform Encephalopathy in Mice
por: Izuo, Naotaka, et al.
Publicado: (2015)

Mitochondrial Cristae Morphology Reflecting Metabolism, Superoxide Formation, Redox Homeostasis, and Pathology
por: Ježek, Petr, et al.
Publicado: (2023)

Formation of the 42-mer Amyloid β Radical and the Therapeutic Role of Superoxide Dismutase in Alzheimer's Disease
por: Murakami, Kazuma, et al.
Publicado: (2011)

Cardiac Electrophysiological Alterations in Heart/Muscle-Specific Manganese-Superoxide Dismutase-Deficient Mice: Prevention by a Dietary Antioxidant Polyphenol
por: Sunagawa, Tadahiro, et al.
Publicado: (2014)

Antioxidant treatment with vitamin C attenuated rotator cuff degeneration caused by oxidative stress in Sod1-deficient mice
por: Morikawa, Daichi, et al.
Publicado: (2018)

Reliable Metabolic Flux Estimation in Escherichia coli Central Carbon Metabolism Using Intracellular Free Amino Acids
por: Okahashi, Nobuyuki, et al.
Publicado: (2014)

Presenilin-2 Mutation Causes Early Amyloid Accumulation and Memory Impairment in a Transgenic Mouse Model of Alzheimer's Disease
por: Toda, Toshihiko, et al.
Publicado: (2011)

Immunochemical characterization on pathological oligomers of mutant Cu/Zn-superoxide dismutase in amyotrophic lateral sclerosis
por: Tokuda, Eiichi, et al.
Publicado: (2017)

Superoxide Dismutases and Superoxide Reductases
por: Sheng, Yuewei, et al.
Publicado: (2014)

Absence of manganese superoxide dismutase delays p53-induced tumor formation()
por: Case, Adam J., et al.
Publicado: (2014)

Corneal endothelial integrity in aging mice lacking superoxide dismutase-1 and/or superoxide dismutase-3
por: Behndig, Anders
Publicado: (2008)

Oxidative Stress Induced Age Dependent Meibomian Gland Dysfunction in Cu, Zn-Superoxide Dismutase-1 (Sod1) Knockout Mice
por: Ibrahim, Osama M. A., et al.
Publicado: (2014)

On the Origin of Superoxide Dismutase: An Evolutionary Perspective of Superoxide-Mediated Redox Signaling
por: Case, Adam J.
Publicado: (2017)

The effects of 3% diquafosol sodium application on the tear functions and ocular surface of the Cu,Zn-superoxide dismutase-1 (Sod1)–knockout mice
por: Kojima, Takashi, et al.
Publicado: (2014)

Apple Procyanidins Suppress Amyloid β-Protein Aggregation
por: Toda, Toshihiko, et al.
Publicado: (2011)

Tempol, a Superoxide Dismutase Mimetic Agent, Inhibits Superoxide Anion-Induced Inflammatory Pain in Mice
por: Bernardy, Catia C. F., et al.
Publicado: (2017)

A mitochondrial superoxide theory for oxidative stress diseases and aging
por: Indo, Hiroko P., et al.
Publicado: (2015)

Lifespan and Glucose Metabolism in Insulin Receptor Mutant Mice
por: Shimizu, Takahiko, et al.
Publicado: (2011)

Glycolysis, but not Mitochondria, responsible for intracellular ATP distribution in cortical area of podocytes
por: Ozawa, Shota, et al.
Publicado: (2015)

Polyoxyethylene‐modified Superoxide Dismutase Reduces Side Effects of Adriamycin and Mitomycin C
por: Kawasaki, Shingo, et al.
Publicado: (1992)

Peculiar Paramecium Hosts Fail to Establish a Stable Intracellular Relationship With Legionella pneumophila
por: Watanabe, Kenta, et al.
Publicado: (2020)

The Effects of 3% Diquafosol Sodium Eye Drops on Tear Function and the Ocular Surface of Cu, Zn-Superoxide Dismutase-1 (Sod1) Knockout Mice Treated with Antiglaucoma Eye Medications
por: Yagi-Yaguchi, Yukari, et al.
Publicado: (2020)

The superoxide anion donor, potassium superoxide, induces pain and inflammation in mice through production of reactive oxygen species and cyclooxygenase-2
por: Maioli, N.A., et al.
Publicado: (2015)

Neonatal Extracellular Superoxide Dismutase Knockout Mice Increase Total Superoxide Dismutase Activity and VEGF Expression after Chronic Hyperoxia
por: Mathias, Maxwell, et al.
Publicado: (2021)

Defunctionalizing intracellular organelles such as mitochondria and peroxisomes with engineered phospholipase A/acyltransferases
por: Watanabe, Satoshi, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_8a45e704775q7ce4sr37c0o0ba