Deciphering hierarchical organization of topologically associated domains through change-point testing

BACKGROUND: The nucleus of eukaryotic cells spatially packages chromosomes into a hierarchical and distinct segregation that plays critical roles in maintaining transcription regulation. High-throughput methods of chromosome conformation capture, such as Hi-C, have revealed topologically associating...

Descripción completa

Detalles Bibliográficos
Autores principales: Xing, Haipeng, Wu, Yingru, Zhang, Michael Q., Chen, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037919/
https://www.ncbi.nlm.nih.gov/pubmed/33838653
http://dx.doi.org/10.1186/s12859-021-04113-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037919/
https://www.ncbi.nlm.nih.gov/pubmed/33838653
http://dx.doi.org/10.1186/s12859-021-04113-8

Ejemplares similares