An Evaluation of the Diagnostic Accuracy of a Panel of Variants in DPYD and a Single Variant in ENOSF1 for Predicting Common Capecitabine Related Toxicities

SIMPLE SUMMARY: 5-Fluorouracil (5-FU) is a chemotherapy drug that can cause severe toxicity in some patients. A protein, an action molecule in our cells, called dihydropyrimidine dehydrogenase, or DPD for short, is important in clearing 5-FU from the body. Some people have versions of DPD that do no...

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Detalles Bibliográficos
Autores principales: Palles, Claire, Fotheringham, Susan, Chegwidden, Laura, Lucas, Marie, Kerr, Rachel, Mozolowski, Guy, Rosmarin, Dan, Taylor, Jenny C., Tomlinson, Ian, Kerr, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037940/
https://www.ncbi.nlm.nih.gov/pubmed/33805100
http://dx.doi.org/10.3390/cancers13071497

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037940/
https://www.ncbi.nlm.nih.gov/pubmed/33805100
http://dx.doi.org/10.3390/cancers13071497

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