The Role of the Receptor Tyrosine Kinase Axl in Carcinogenesis and Development of Therapeutic Resistance: An Overview of Molecular Mechanisms and Future Applications

SIMPLE SUMMARY: The tyrosine kinase receptor Axl is an oncogene that promotes cancer development by increasing proliferation, survival, invasion, and migration in cancer cells. Axl also contributes to the development of resistance to chemo-, radio-, immune- and targeted therapy in many cancer types....

Descripción completa

Detalles Bibliográficos
Autores principales: Wium, Martha, Ajayi-Smith, Aderonke F., Paccez, Juliano D., Zerbini, Luiz F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037968/
https://www.ncbi.nlm.nih.gov/pubmed/33806258
http://dx.doi.org/10.3390/cancers13071521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037968/
https://www.ncbi.nlm.nih.gov/pubmed/33806258
http://dx.doi.org/10.3390/cancers13071521

Ejemplares similares