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Configurational Entropy of Folded Proteins and Its Importance for Intrinsically Disordered Proteins

Many pairwise additive force fields are in active use for intrinsically disordered proteins (IDPs) and regions (IDRs), some of which modify energetic terms to improve the description of IDPs/IDRs but are largely in disagreement with solution experiments for the disordered states. This work considers...

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Detalles Bibliográficos
Autores principales: Liu, Meili, Das, Akshaya K., Lincoff, James, Sasmal, Sukanya, Cheng, Sara Y., Vernon, Robert M., Forman-Kay, Julie D., Head-Gordon, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037987/
https://www.ncbi.nlm.nih.gov/pubmed/33810353
http://dx.doi.org/10.3390/ijms22073420