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Collagen I Modifies Connexin-43 Hemichannel Activity via Integrin α2β1 Binding in TGFβ1-Evoked Renal Tubular Epithelial Cells

Chronic Kidney Disease (CKD) is associated with sustained inflammation and progressive fibrosis, changes that have been linked to altered connexin hemichannel-mediated release of adenosine triphosphate (ATP). Kidney fibrosis develops in response to increased deposition of extracellular matrix (ECM),...

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Detalles Bibliográficos
Autores principales: Potter, Joe A., Price, Gareth W., Cliff, Chelsy L., Green, Colin R., Squires, Paul E., Hills, Claire E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038016/
https://www.ncbi.nlm.nih.gov/pubmed/33807408
http://dx.doi.org/10.3390/ijms22073644