Cargando…
Collagen I Modifies Connexin-43 Hemichannel Activity via Integrin α2β1 Binding in TGFβ1-Evoked Renal Tubular Epithelial Cells
Chronic Kidney Disease (CKD) is associated with sustained inflammation and progressive fibrosis, changes that have been linked to altered connexin hemichannel-mediated release of adenosine triphosphate (ATP). Kidney fibrosis develops in response to increased deposition of extracellular matrix (ECM),...
Autores principales: | Potter, Joe A., Price, Gareth W., Cliff, Chelsy L., Green, Colin R., Squires, Paul E., Hills, Claire E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038016/ https://www.ncbi.nlm.nih.gov/pubmed/33807408 http://dx.doi.org/10.3390/ijms22073644 |
Ejemplares similares
-
Connexin-43 hemichannels orchestrate NOD-like receptor protein-3 (NLRP3) inflammasome activation and sterile inflammation in tubular injury
por: Roger, Elena, et al.
Publicado: (2023) -
Blocking connexin 43 hemichannel‐mediated ATP release reduces communication within and between tubular epithelial cells and medullary fibroblasts in a model of diabetic nephropathy
por: Williams, Bethany M., et al.
Publicado: (2022) -
Blocking Connexin-43 mediated hemichannel activity protects against early tubular injury in experimental chronic kidney disease
por: Price, Gareth W., et al.
Publicado: (2020) -
Connexin43 Hemichannel-Mediated Regulation of Connexin43
por: Li, Kai, et al.
Publicado: (2013) -
Connexin 43: A Target for the Treatment of Inflammation in Secondary Complications of the Kidney and Eye in Diabetes
por: Cliff, Chelsy L., et al.
Publicado: (2022)