The Collagen-Modifying Enzyme PLOD2 Is Induced and Required during L1-Mediated Colon Cancer Progression

The overactivation of Wnt/β-catenin signaling is a hallmark of colorectal cancer (CRC) development. We identified the cell adhesion molecule L1CAM (L1) as a target of β-catenin-TCF transactivation in CRC cells. The overexpression of L1 in CRC cells confers enhanced proliferation, motility, tumorigen...

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Detalles Bibliográficos
Autores principales: Cheriyamundath, Sanith, Kumar, Anmol, Gavert, Nancy, Brabletz, Thomas, Ben-Ze’ev, Avri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038063/
https://www.ncbi.nlm.nih.gov/pubmed/33805564
http://dx.doi.org/10.3390/ijms22073552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038063/
https://www.ncbi.nlm.nih.gov/pubmed/33805564
http://dx.doi.org/10.3390/ijms22073552

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