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Possibility for Transcriptional Targeting of Cancer-Associated Fibroblasts—Limitations and Opportunities

Cancer-associated fibroblasts (CAF) are attractive therapeutic targets in the tumor microenvironment. The possibility of using CAFs as a source of therapeutic molecules is a challenging approach in gene therapy. This requires transcriptional targeting of transgene expression by cis-regulatory elemen...

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Detalles Bibliográficos
Autores principales: Antonova, Dina V., Zinovyeva, Marina V., Kondratyeva, Liya G., Sass, Alexander V., Alekseenko, Irina V., Pleshkan, Victor V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038081/
https://www.ncbi.nlm.nih.gov/pubmed/33804861
http://dx.doi.org/10.3390/ijms22073298