Cargando…
Possibility for Transcriptional Targeting of Cancer-Associated Fibroblasts—Limitations and Opportunities
Cancer-associated fibroblasts (CAF) are attractive therapeutic targets in the tumor microenvironment. The possibility of using CAFs as a source of therapeutic molecules is a challenging approach in gene therapy. This requires transcriptional targeting of transgene expression by cis-regulatory elemen...
Autores principales: | Antonova, Dina V., Zinovyeva, Marina V., Kondratyeva, Liya G., Sass, Alexander V., Alekseenko, Irina V., Pleshkan, Victor V. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038081/ https://www.ncbi.nlm.nih.gov/pubmed/33804861 http://dx.doi.org/10.3390/ijms22073298 |
Ejemplares similares
-
Spheroids of FAP-Positive Cell Lines as a Model for Screening Drugs That Affect FAP Expression
por: Pleshkan, Victor V., et al.
Publicado: (2023) -
Searching for Promoters to Drive Stable and Long-Term Transgene Expression in Fibroblasts for Syngeneic Mouse Tumor Models
por: Antonova, Dina V., et al.
Publicado: (2020) -
Promoters with Cancer Cell-Specific Activity for Melanoma Gene Therapy
por: Pleshkan, V.V., et al.
Publicado: (2011) -
Step-by-Step Immune Activation for Suicide Gene Therapy Reinforcement
por: Alekseenko, Irina, et al.
Publicado: (2021) -
Novel Histone-Based DNA Carrier Targeting Cancer-Associated Fibroblasts
por: Kuzmich, Alexey, et al.
Publicado: (2020)