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Diphenyl-Methane Based Thyromimetic Inhibitors for Transthyretin Amyloidosis

Thyromimetics, whose physicochemical characteristics are analog to thyroid hormones (THs) and their derivatives, are promising candidates as novel therapeutics for neurodegenerative and metabolic pathologies. In particular, sobetirome (GC-1), one of the initial halogen-free thyromimetics, and newly...

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Detalles Bibliográficos
Autores principales: Kim, Bokyung, Ko, Young Ho, Runfola, Massimiliano, Rapposelli, Simona, Ortore, Gabriella, Chiellini, Grazia, Kim, Jin Hae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038088/
https://www.ncbi.nlm.nih.gov/pubmed/33800546
http://dx.doi.org/10.3390/ijms22073488