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Diphenyl-Methane Based Thyromimetic Inhibitors for Transthyretin Amyloidosis
Thyromimetics, whose physicochemical characteristics are analog to thyroid hormones (THs) and their derivatives, are promising candidates as novel therapeutics for neurodegenerative and metabolic pathologies. In particular, sobetirome (GC-1), one of the initial halogen-free thyromimetics, and newly...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038088/ https://www.ncbi.nlm.nih.gov/pubmed/33800546 http://dx.doi.org/10.3390/ijms22073488 |