Replacing the Z-phenyl Ring in Tamoxifen(®) with a para-Connected NCN Pincer-Pt-Cl Grouping by Post-Modification †

Post-modification of a series of NCN-pincer platinum(II) complexes [PtX(NCN-R-4)] (NCN = [C(6)H(2)(CH(2)NMe(2))(2)-2,6](–), R = C(O)H, C(O)Me and C(O)Et), X = Cl(–) or Br(–)) at the para-position using the McMurry reaction was studied. The synthetic route towards two new [PtCl(NCN-R-4)] (R = C(O)Me...

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Detalles Bibliográficos
Autores principales: Batema, Guido D., Korstanje, Ties J., Guillena, Gabriela, Rodríguez, Gema, Lutz, Martin, van Klink, Gerard P. M., Gossage, Robert A., van Koten, Gerard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038112/
https://www.ncbi.nlm.nih.gov/pubmed/33810499
http://dx.doi.org/10.3390/molecules26071888

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038112/
https://www.ncbi.nlm.nih.gov/pubmed/33810499
http://dx.doi.org/10.3390/molecules26071888

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