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Replacing the Z-phenyl Ring in Tamoxifen(®) with a para-Connected NCN Pincer-Pt-Cl Grouping by Post-Modification †
Post-modification of a series of NCN-pincer platinum(II) complexes [PtX(NCN-R-4)] (NCN = [C(6)H(2)(CH(2)NMe(2))(2)-2,6](–), R = C(O)H, C(O)Me and C(O)Et), X = Cl(–) or Br(–)) at the para-position using the McMurry reaction was studied. The synthetic route towards two new [PtCl(NCN-R-4)] (R = C(O)Me...
Autores principales: | Batema, Guido D., Korstanje, Ties J., Guillena, Gabriela, Rodríguez, Gema, Lutz, Martin, van Klink, Gerard P. M., Gossage, Robert A., van Koten, Gerard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038112/ https://www.ncbi.nlm.nih.gov/pubmed/33810499 http://dx.doi.org/10.3390/molecules26071888 |
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