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Metformin Inhibits the Urea Cycle and Reduces Putrescine Generation in Colorectal Cancer Cell Lines

The urea cycle (UC) removes the excess nitrogen and ammonia generated by nitrogen-containing compound composites or protein breakdown in the human body. Research has shown that changes in UC enzymes are not only related to tumorigenesis and tumor development but also associated with poor survival in...

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Detalles Bibliográficos
Autores principales: Zhang, Tao, Hu, Ling, Tang, Jia-Feng, Xu, Hang, Tian, Kuan, Wu, Meng-Na, Huang, Shi-Ying, Du, Yu-Mei, Zhou, Peng, Lu, Rui-Jin, He, Shuang, Xu, Jia-Mei, Si, Jian-Jun, Li, Jing, Chen, Di-Long, Ran, Jian-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038129/
https://www.ncbi.nlm.nih.gov/pubmed/33915902
http://dx.doi.org/10.3390/molecules26071990