NCX-4040, a Unique Nitric Oxide Donor, Induces Reversal of Drug-Resistance in Both ABCB1- and ABCG2-Expressing Multidrug Human Cancer Cells

SIMPLE SUMMARY: Development of resistance to chemotherapeutics during the treatment of human cancers is a serious problem in the clinic, resulting in a poor treatment outcome and survival. It is believed that overexpression of ABC efflux proteins (e.g., P-gp/ABCB1, BCRP/ABCG2 and MRP/ABCC1) on the t...

Descripción completa

Detalles Bibliográficos
Autores principales: Sinha, Birandra K., Perera, Lalith, Cannon, Ronald E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038154/
https://www.ncbi.nlm.nih.gov/pubmed/33918289
http://dx.doi.org/10.3390/cancers13071680

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038154/
https://www.ncbi.nlm.nih.gov/pubmed/33918289
http://dx.doi.org/10.3390/cancers13071680

Ejemplares similares