Analysis of Missense Variants in the Human Histamine Receptor Family Reveals Increased Constitutive Activity of E410(6.30×30)K Variant in the Histamine H(1) Receptor

The Exome Aggregation Consortium has collected the protein-encoding DNA sequences of almost 61,000 unrelated humans. Analysis of this dataset for G protein-coupled receptor (GPCR) proteins (available at GPCRdb) revealed a total of 463 naturally occurring genetic missense variations in the histamine...

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Detalles Bibliográficos
Autores principales: Ma, Xiaoyuan, Segura, Marta Arimont, Zarzycka, Barbara, Vischer, Henry F., Leurs, Rob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038156/
https://www.ncbi.nlm.nih.gov/pubmed/33918180
http://dx.doi.org/10.3390/ijms22073702

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038156/
https://www.ncbi.nlm.nih.gov/pubmed/33918180
http://dx.doi.org/10.3390/ijms22073702

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