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Chronically Elevated Exogenous Glucose Elicits Antipodal Effects on the Proteome Signature of Differentiating Human iPSC-Derived Pancreatic Progenitors

The past decade revealed that cell identity changes, such as dedifferentiation or transdifferentiation, accompany the insulin-producing β-cell decay in most diabetes conditions. Mapping and controlling the mechanisms governing these processes is, thus, extremely valuable for managing the disease pro...

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Detalles Bibliográficos
Autores principales: Ghila, Luiza, Legøy, Thomas Aga, Mathisen, Andreas Frøslev, Abadpour, Shadab, Paulo, Joao A., Scholz, Hanne, Ræder, Helge, Chera, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038174/
https://www.ncbi.nlm.nih.gov/pubmed/33918250
http://dx.doi.org/10.3390/ijms22073698