Differential Cytotoxicity Mechanisms of Copper Complexed with Disulfiram in Oral Cancer Cells

Disulfiram (DSF), an irreversible aldehyde dehydrogenase inhibitor, is being used in anticancer therapy, as its effects in humans are known and less adverse than conventional chemotherapy. We explored the potential mechanism behind the cytotoxicity of DSF-Cu(+)/Cu(2+) complexes in oral epidermoid ca...

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Detalles Bibliográficos
Autores principales: Chen, Ssu-Yu, Chang, Yung-Lung, Liu, Shu-Ting, Chen, Gunng-Shinng, Lee, Shiao-Pieng, Huang, Shih-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038175/
https://www.ncbi.nlm.nih.gov/pubmed/33918312
http://dx.doi.org/10.3390/ijms22073711

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038175/
https://www.ncbi.nlm.nih.gov/pubmed/33918312
http://dx.doi.org/10.3390/ijms22073711

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