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Differential Cytotoxicity Mechanisms of Copper Complexed with Disulfiram in Oral Cancer Cells
Disulfiram (DSF), an irreversible aldehyde dehydrogenase inhibitor, is being used in anticancer therapy, as its effects in humans are known and less adverse than conventional chemotherapy. We explored the potential mechanism behind the cytotoxicity of DSF-Cu(+)/Cu(2+) complexes in oral epidermoid ca...
Autores principales: | Chen, Ssu-Yu, Chang, Yung-Lung, Liu, Shu-Ting, Chen, Gunng-Shinng, Lee, Shiao-Pieng, Huang, Shih-Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038175/ https://www.ncbi.nlm.nih.gov/pubmed/33918312 http://dx.doi.org/10.3390/ijms22073711 |
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