In Silico Identification of Small Molecules as New Cdc25 Inhibitors through the Correlation between Chemosensitivity and Protein Expression Pattern

The cell division cycle 25 (Cdc25) protein family plays a crucial role in controlling cell proliferation, making it an excellent target for cancer therapy. In this work, a set of small molecules were identified as Cdc25 modulators by applying a mixed ligand-structure-based approach and taking advant...

Descripción completa

Detalles Bibliográficos
Autores principales: Lauria, Antonino, Martorana, Annamaria, La Monica, Gabriele, Mannino, Salvatore, Mannino, Giuseppe, Peri, Daniele, Gentile, Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038176/
https://www.ncbi.nlm.nih.gov/pubmed/33918281
http://dx.doi.org/10.3390/ijms22073714

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038176/
https://www.ncbi.nlm.nih.gov/pubmed/33918281
http://dx.doi.org/10.3390/ijms22073714

Ejemplares similares