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Experimental and Computational Studies on Structure and Energetic Properties of Halogen Derivatives of 2-Deoxy-D-Glucose

The results of structural studies on a series of halogen-substituted derivatives of 2-deoxy-D-glucose (2-DG) are reported. 2-DG is an inhibitor of glycolysis, a metabolic pathway crucial for cancer cell proliferation and viral replication in host cells, and interferes with D-glucose and D-mannose me...

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Detalles Bibliográficos
Autores principales: Ziemniak, Marcin, Zawadzka-Kazimierczuk, Anna, Pawlędzio, Sylwia, Malinska, Maura, Sołtyka, Maja, Trzybiński, Damian, Koźmiński, Wiktor, Skora, Stanisław, Zieliński, Rafał, Fokt, Izabela, Priebe, Waldemar, Woźniak, Krzysztof, Pająk, Beata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038202/
https://www.ncbi.nlm.nih.gov/pubmed/33918425
http://dx.doi.org/10.3390/ijms22073720