Development of a Multimatrix UHPLC-MS/MS Method for the Determination of Paracetamol and Its Metabolites in Animal Tissues

Paracetamol/acetaminophen (APAP) is one of the most popular pharmacologically active substances used as an analgesic and antipyretic agent. The metabolism of this drug occurs in the liver and leads to the formation of two main metabolites—glucuronic acid and sulfate derivate. Despite the wide use of...

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Detalles Bibliográficos
Autores principales: Pietruk, Konrad, Gbylik-Sikorska, Małgorzata, Łebkowska-Wieruszewska, Beata, Gajda, Anna, Giorgi, Mario, Sartini, Irene, Jedziniak, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038326/
https://www.ncbi.nlm.nih.gov/pubmed/33918518
http://dx.doi.org/10.3390/molecules26072046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038326/
https://www.ncbi.nlm.nih.gov/pubmed/33918518
http://dx.doi.org/10.3390/molecules26072046

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