Discovery of a Novel Acetylcholinesterase Inhibitor by Fragment-Based Design and Virtual Screening

Despite extensive and intensive research efforts in recent decades, there is still no effective treatment for neurodegenerative diseases. On this background, the use of drugs inhibiting the enzyme acetylcholinesterase (AChE) remains an eternal evergreen in the symptomatic treatment of mild to modera...

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Detalles Bibliográficos
Autores principales: Stavrakov, Georgi, Philipova, Irena, Lukarski, Atanas, Atanasova, Mariyana, Georgiev, Borislav, Atanasova, Teodora, Konstantinov, Spiro, Doytchinova, Irini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038331/
https://www.ncbi.nlm.nih.gov/pubmed/33916760
http://dx.doi.org/10.3390/molecules26072058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038331/
https://www.ncbi.nlm.nih.gov/pubmed/33916760
http://dx.doi.org/10.3390/molecules26072058

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