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GT-Repeat Polymorphism in the HO-1 Gene Promoter Is Associated with Risk of Liver Cancer: A Follow-Up Study from Arseniasis-Endemic Areas in Taiwan

The induction of heme oxygenase-1 (HO-1) has been shown to have therapeutic potential in experimental models of hepatitis and liver fibrosis, which are closely related to liver cancer. In humans, HO-1 induction is transcriptionally modulated by the length of a GT-repeat [(GT)n] in the promoter regio...

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Detalles Bibliográficos
Autores principales: Wu, Meei-Maan, Hsieh, Fang-I, Hsu, Ling-I, Lee, Te-Chang, Chiou, Hung-Yi, Chen, Chien-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038349/
https://www.ncbi.nlm.nih.gov/pubmed/33916685
http://dx.doi.org/10.3390/jcm10071489