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RAD51 Inhibition Induces R-Loop Formation in Early G1 Phase of the Cell Cycle

R-loops are three-stranded structures generated by annealing of nascent transcripts to the template DNA strand, leaving the non-template DNA strand exposed as a single-stranded loop. Although R-loops play important roles in physiological processes such as regulation of gene expression, mitochondrial...

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Detalles Bibliográficos
Autores principales: Nascakova, Zuzana, Boleslavska, Barbora, Urban, Vaclav, Oravetzova, Anna, Vlachova, Edita, Janscak, Pavel, Dobrovolna, Jana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038378/
https://www.ncbi.nlm.nih.gov/pubmed/33916766
http://dx.doi.org/10.3390/ijms22073740