Modeling Rett Syndrome with Human Pluripotent Stem Cells: Mechanistic Outcomes and Future Clinical Perspectives

Rett syndrome (RTT) is a neurodevelopmental disorder caused by mutations in the gene encoding the methyl-CpG-binding protein 2 (MeCP2). Among many different roles, MeCP2 has a high phenotypic impact during the different stages of brain development. Thus, it is essential to intensively investigate th...

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Detalles Bibliográficos
Autores principales: Gomes, Ana Rita, Fernandes, Tiago G., Cabral, Joaquim M.S., Diogo, Maria Margarida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038474/
https://www.ncbi.nlm.nih.gov/pubmed/33916879
http://dx.doi.org/10.3390/ijms22073751

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038474/
https://www.ncbi.nlm.nih.gov/pubmed/33916879
http://dx.doi.org/10.3390/ijms22073751

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