RGD-Binding Integrins Revisited: How Recently Discovered Functions and Novel Synthetic Ligands (Re-)Shape an Ever-Evolving Field

SIMPLE SUMMARY: Integrins, a superfamily of cell adhesion receptors, were extensively investigated as therapeutic targets over the last decades, motivated by their multiple functions, e.g., in cancer (progression, metastasis, angiogenesis), sepsis, fibrosis, and viral infections. Although integrin-t...

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Detalles Bibliográficos
Autores principales: Ludwig, Beatrice S., Kessler, Horst, Kossatz, Susanne, Reuning, Ute
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038522/
https://www.ncbi.nlm.nih.gov/pubmed/33916607
http://dx.doi.org/10.3390/cancers13071711

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038522/
https://www.ncbi.nlm.nih.gov/pubmed/33916607
http://dx.doi.org/10.3390/cancers13071711

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