Inhibition of Liver Metastasis in Colorectal Cancer by Targeting IL-13/IL13Rα2 Binding Site with Specific Monoclonal Antibodies

SIMPLE SUMMARY: IL13Rα2 has been repeatedly reported as an excellent therapeutic target for multiple types of advanced cancers. However, previous IL13Rα2 targeting attempts have been mostly unsuccessful. Here, we describe a novel strategy based on the blocking of the IL-13 tumorigenic activity using...

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Detalles Bibliográficos
Autores principales: Jaén, Marta, Bartolomé, Rubén A., Aizpurua, Carmen, Martin-Regalado, Ángela, Imbaud, J. Ignacio, Casal, J. Ignacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038733/
https://www.ncbi.nlm.nih.gov/pubmed/33917458
http://dx.doi.org/10.3390/cancers13071731

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038733/
https://www.ncbi.nlm.nih.gov/pubmed/33917458
http://dx.doi.org/10.3390/cancers13071731

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