Novel and Potent Small Molecules against Melanoma Harboring BRAF Class I/II/III Mutants for Overcoming Drug Resistance

Melanoma accounts for the majority of skin cancer deaths. About 50% of all melanomas are associated with BRAF mutations. BRAF mutations are classified into three classes with regard to dependency on RAF dimerization and RAS signaling. The most frequently occurring class I BRAF V600 mutations are sen...

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Detalles Bibliográficos
Autores principales: Kim, Namkyoung, Shin, Injae, Lee, Jiwon, Jeon, Eunhye, Kim, Younghoon, Ryu, Seongshick, Ju, Eunhye, Cho, Wonjeong, Sim, Taebo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038755/
https://www.ncbi.nlm.nih.gov/pubmed/33917428
http://dx.doi.org/10.3390/ijms22073783

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038755/
https://www.ncbi.nlm.nih.gov/pubmed/33917428
http://dx.doi.org/10.3390/ijms22073783

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