Circulating Tumor DNA Reflects Uveal Melanoma Responses to Protein Kinase C Inhibition

SIMPLE SUMMARY: Uveal melanoma (UM) is a rare cancer, with no effective standard systemic therapy in the metastatic setting. Over 95% of UM harbor activating driver mutations that can be detected in the circulation. In this study, circulating tumor DNA (ctDNA) was measured in 17 metastatic UM patien...

Descripción completa

Detalles Bibliográficos
Autores principales: Park, John J., Diefenbach, Russell J., Byrne, Natalie, Long, Georgina V., Scolyer, Richard A., Gray, Elin S., Carlino, Matteo S., Rizos, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038771/
https://www.ncbi.nlm.nih.gov/pubmed/33917514
http://dx.doi.org/10.3390/cancers13071740

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038771/
https://www.ncbi.nlm.nih.gov/pubmed/33917514
http://dx.doi.org/10.3390/cancers13071740

Ejemplares similares