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Circulating Tumor DNA Reflects Uveal Melanoma Responses to Protein Kinase C Inhibition

SIMPLE SUMMARY: Uveal melanoma (UM) is a rare cancer, with no effective standard systemic therapy in the metastatic setting. Over 95% of UM harbor activating driver mutations that can be detected in the circulation. In this study, circulating tumor DNA (ctDNA) was measured in 17 metastatic UM patien...

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Detalles Bibliográficos
Autores principales:	Park, John J., Diefenbach, Russell J., Byrne, Natalie, Long, Georgina V., Scolyer, Richard A., Gray, Elin S., Carlino, Matteo S., Rizos, Helen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038771/ https://www.ncbi.nlm.nih.gov/pubmed/33917514 http://dx.doi.org/10.3390/cancers13071740

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