Butyrate Suppresses Glucose Metabolism of Colorectal Cancer Cells via GPR109a-AKT Signaling Pathway and Enhances Chemotherapy

Glycolysis inhibitors are promising therapeutic drugs for tumor treatment, which target the uniquely elevated glucose metabolism of cancer cells. Butyrate is a critical product of beneficial microbes in the colon, which exerts extraordinary anti-cancer activities. In particular, butyrate shows biase...

Descripción completa

Detalles Bibliográficos
Autores principales: Geng, Hong-Wei, Yin, Feng-Yi, Zhang, Zhi-Fa, Gong, Xu, Yang, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039130/
https://www.ncbi.nlm.nih.gov/pubmed/33855046
http://dx.doi.org/10.3389/fmolb.2021.634874

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039130/
https://www.ncbi.nlm.nih.gov/pubmed/33855046
http://dx.doi.org/10.3389/fmolb.2021.634874

Ejemplares similares