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Butyrate Suppresses Glucose Metabolism of Colorectal Cancer Cells via GPR109a-AKT Signaling Pathway and Enhances Chemotherapy
Glycolysis inhibitors are promising therapeutic drugs for tumor treatment, which target the uniquely elevated glucose metabolism of cancer cells. Butyrate is a critical product of beneficial microbes in the colon, which exerts extraordinary anti-cancer activities. In particular, butyrate shows biase...
Autores principales: | Geng, Hong-Wei, Yin, Feng-Yi, Zhang, Zhi-Fa, Gong, Xu, Yang, Yun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039130/ https://www.ncbi.nlm.nih.gov/pubmed/33855046 http://dx.doi.org/10.3389/fmolb.2021.634874 |
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