Direct and Indirect Modulation of T Cells by VEGF-A Counteracted by Anti-Angiogenic Treatment

Vascular endothelial growth factor A is known to play a central role in tumor angiogenesis. Several studies showed that VEGF-A is also an immunosuppressive factor. In tumor-bearing hosts, VEGF-A can modulate immune cells (DC, MDSC, TAM) to induce the accumulation of regulatory T-cells while simultan...

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Detalles Bibliográficos
Autores principales: Bourhis, Morgane, Palle, Juliette, Galy-Fauroux, Isabelle, Terme, Magali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039365/
https://www.ncbi.nlm.nih.gov/pubmed/33854498
http://dx.doi.org/10.3389/fimmu.2021.616837

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039365/
https://www.ncbi.nlm.nih.gov/pubmed/33854498
http://dx.doi.org/10.3389/fimmu.2021.616837

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