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Making Insulin and Staying Out of Autoimmune Trouble: The Beta-Cell Conundrum
Autoimmune type 1 diabetes (T1D) results from the intricate crosstalk of various immune cell types. CD8+ T cells dominate the pro-inflammatory milieu of islet infiltration (insulitis), and are considered as key effectors of beta-cell destruction, through the recognition of MHC Class I-peptide comple...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039383/ https://www.ncbi.nlm.nih.gov/pubmed/33854508 http://dx.doi.org/10.3389/fimmu.2021.639682 |