Methods and Techniques to Facilitate the Development of Clostridium novyi NT as an Effective, Therapeutic Oncolytic Bacteria

The tumor microenvironment is characterized by anomalous vascularization, hypoxia, and acidity at the core of solid tumors that culminates in concentrated necrosis and immune system dysregulation among other effects. While this environment presents several challenges for the development of oncothera...

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Detalles Bibliográficos
Autores principales: Dailey, Kaitlin M., Jacobson, Reed I., Johnson, Paige R., Woolery, Taylor J., Kim, Jiha, Jansen, Rick J., Mallik, Sanku, Brooks, Amanda E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039391/
https://www.ncbi.nlm.nih.gov/pubmed/33854487
http://dx.doi.org/10.3389/fmicb.2021.624618

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039391/
https://www.ncbi.nlm.nih.gov/pubmed/33854487
http://dx.doi.org/10.3389/fmicb.2021.624618

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