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Compliant Substrates Enhance Macrophage Cytokine Release and NLRP3 Inflammasome Formation During Their Pro-Inflammatory Response

Immune cells process a myriad of biochemical signals but their function and behavior are also determined by mechanical cues. Macrophages are no exception to this. Being present in all types of tissues, macrophages are exposed to environments of varying stiffness, which can be further altered under p...

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Detalles Bibliográficos
Autores principales: Escolano, Joan-Carles, Taubenberger, Anna V., Abuhattum, Shada, Schweitzer, Christine, Farrukh, Aleeza, del Campo, Aránzazu, Bryant, Clare E., Guck, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039395/
https://www.ncbi.nlm.nih.gov/pubmed/33855019
http://dx.doi.org/10.3389/fcell.2021.639815