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Identification of intermediate conformations in the photocycle of the light-driven sodium-pumping rhodopsin KR2

The light-driven rhodopsin KR2 transports Na(+)via the M- and O-states. However, the mechanisms by which the retinal regulates Na(+) pumping is unknown, in part because KR2 adopts both pentamer and monomer forms in crystal structures and in part because these structures show differences in the prote...

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Detalles Bibliográficos
Autores principales: Tsujimura, Masaki, Ishikita, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039564/
https://www.ncbi.nlm.nih.gov/pubmed/33639164
http://dx.doi.org/10.1016/j.jbc.2021.100459