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Mismatch repair deficiency occurs very rarely in seminomas

BACKGROUND: Dense tumor-associated lymphocyte infiltration is linked to mismatch repair (MMR) deficiency in colorectal and endometrial cancer. MMR deficiency is of high clinical importance as MMR deficient cancers tend to react favorably to treatment with immune checkpoint inhibitors. Strong lymphoc...

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Detalles Bibliográficos
Autores principales: Dum, David, Steurer, Stefan, Simon, Ronald, Zimmermann, Pia Victoria, Burandt, Eike, Clauditz, Till Sebastian, Fisch, Margit, Rink, Michael, Dahlem, Roland, Höppner, Wolfgang, Zecha, Henrik, Doh, Ousman, Matthies, Cord, Wilczak, Waldemar, Sauter, Guido, Fraune, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039613/
https://www.ncbi.nlm.nih.gov/pubmed/33850739
http://dx.doi.org/10.21037/tau-20-1355