Roxithromycin attenuates inflammation via modulation of RAGE-influenced calprotectin expression in a neutrophilic asthma model

BACKGROUND: Roxithromycin (RXM), a macrolide antibiotic, exhibits anti-asthmatic effects, but its specific mechanism of action remains elusive. We evaluated the effects of RXM on airway inflammation, the expression of calprotectin, and the activity of the receptor of advanced glycation end products...

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Detalles Bibliográficos
Autores principales: Gu, Xiaofei, Shu, Danni, Ying, Songmin, Dai, Yuanrong, Zhang, Qi, Chen, Xinmiao, Chen, Huijun, Dai, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039670/
https://www.ncbi.nlm.nih.gov/pubmed/33850891
http://dx.doi.org/10.21037/atm-21-859

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039670/
https://www.ncbi.nlm.nih.gov/pubmed/33850891
http://dx.doi.org/10.21037/atm-21-859

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