Constitutive activation of ERK1/2 signaling protects against myocardial ischemia via inhibition of mitochondrial fragmentation in the aging heart

BACKGROUND: Studies have shown that the ability of the myocardium to tolerate ischemia becomes significantly compromised with age. During ischemia, several endogenous protective signals are activated to protect the heart from injury, among which extracellular-signal regulated kinase (ERK) 1/2 signal...

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Detalles Bibliográficos
Autores principales: Zhao, Qiang, Liu, Fen, Zhao, Qian, Zhang, Jinyu, Luo, Junyi, Li, Xiaomei, Yang, Yining
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039677/
https://www.ncbi.nlm.nih.gov/pubmed/33850876
http://dx.doi.org/10.21037/atm-21-503

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039677/
https://www.ncbi.nlm.nih.gov/pubmed/33850876
http://dx.doi.org/10.21037/atm-21-503

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