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Analysis of metabolic network disruption in engineered microbial hosts due to enzyme promiscuity

Increasing understanding of metabolic and regulatory networks underlying microbial physiology has enabled creation of progressively more complex synthetic biological systems for biochemical, biomedical, agricultural, and environmental applications. However, despite best efforts, confounding phenotyp...

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Detalles Bibliográficos
Autores principales: Porokhin, Vladimir, Amin, Sara A., Nicks, Trevor B., Gopinarayanan, Venkatesh Endalur, Nair, Nikhil U., Hassoun, Soha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039717/
https://www.ncbi.nlm.nih.gov/pubmed/33850714
http://dx.doi.org/10.1016/j.mec.2021.e00170