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Opa1 relies on cristae preservation and ATP synthase to curtail reactive oxygen species accumulation in mitochondria

Reactive oxygen species (ROS) are a common product of active mitochondrial respiration carried in mitochondrial cristae, but whether cristae shape influences ROS levels is unclear. Here we report that the mitochondrial fusion and cristae shape protein Opa1 requires mitochondrial ATP synthase oligome...

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Detalles Bibliográficos
Autores principales: Quintana-Cabrera, Rubén, Manjarrés-Raza, Israel, Vicente-Gutiérrez, Carlos, Corrado, Mauro, Bolaños, Juan P., Scorrano, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039725/
https://www.ncbi.nlm.nih.gov/pubmed/33780775
http://dx.doi.org/10.1016/j.redox.2021.101944