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Chemical complementarity between immune receptors and cancer mutants, independent of antigen presentation protein binding, is associated with increased survival rates

Uterine cancer has been associated with a T-cell immune response that leads to increased survival. Therefore, we used several bioinformatics approaches to explore specific interactions between T-cell receptor (TCR) and tumor mutant peptide sequences. Using endometrioid uterine cancer exome files fro...

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Detalles Bibliográficos
Autores principales: Hsiang, Monica, Chobrutskiy, Boris I., Diaz, Michael, Huda, Taha I., Creadore, Stefan, Zaman, Saif, Cios, Konrad J., Gozlan, Etienne C., Blanck, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039726/
https://www.ncbi.nlm.nih.gov/pubmed/33780706
http://dx.doi.org/10.1016/j.tranon.2021.101069