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Identification of the canonical and noncanonical role of miR-143/145 in estrogen-deficient bone loss

Rationale: Postmenopausal-induced bone loss is mainly caused by declining core transcription factors (TFs) of bone mesenchymal stem cells (BMSCs), but little is known about how miRNAs regulate chromatin structure remodeling of TFs gene to maintain BMSCs function in bone homeostasis. Methods: We exam...

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Detalles Bibliográficos
Autores principales: Xu, Rongyao, Shen, Xin, Xie, Hanyu, Zhang, Hengguo, Liu, Dingshan, Chen, Xin, Fu, Yu, Zhang, Ping, Yang, Yi, Cheng, Jie, Jiang, Hongbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039936/
https://www.ncbi.nlm.nih.gov/pubmed/33859759
http://dx.doi.org/10.7150/thno.55041